Therapeutic Effects of Probiotic Pediococcus acidilactici CNCM MA 18/5 (Bactocell PA) via Modulation of Oxidative Stress and Inflammatory Pathways in Streptozotosin Induced Diabetic Rats

Betul Apaydin Yildirim, Enes Tercanli, Kubra Asena Terim Kapakin, Tuba Karaarslan, Mustafa Atasever · 2026

Read Therapeutic Effects of Probiotic Pediococcus acidilactici CNCM MA 18/5 (Bactocell PA) via Modulation of Oxidative Stress and Inflammatory Pathways in Streptozotosin Induced Diabetic Rats by Betul Apaydin Yildirim, Enes Tercanli, Kubra Asena Terim Kapakin, Tuba Karaarslan, Mustafa Atasever (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13240053.txt.

Description

Betul Apaydin Yildirim and colleagues tested a probiotic bacterium as a treatment for diabetes in rats, in a study published in twenty twenty-six. Diabetes was triggered with a standard drug, and treated animals received milk fermented with the probiotic each day for about three weeks. The team compared blood sugar, long-term sugar control, insulin, and signs of tissue damage and inflammation in the pancreas across five groups of animals. They also checked which stress and defense genes were switched on.

Diabetic rats given the probiotic had lower blood sugar and lower long-term sugar readings than untreated diabetic rats. Insulin rose, damage markers and inflammatory signals fell, and protective antioxidant enzymes worked better. Gene patterns shifted in the same helpful direction. Tissue examination supported the blood results. The authors call the strain a promising candidate, while noting the work is early and in animals.

Catalog record

CREATORBetul Apaydin Yildirim, Enes Tercanli, Kubra Asena Terim Kapakin, Tuba Karaarslan, Mustafa Atasever
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13240053

Browse the full library · About the Tower of Babel