Recent advances in piperine and its derivatives as potential anticancer agents
Qi-Hua Yu, Zhiyan Liu, Jiazheng Liu, Li-Ping Bai · 2026
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Description
Qi-Hua Yu and colleagues review recent work on piperine, the pungent compound in black pepper, as a possible cancer drug source in a 2026 article. Interest is high, yet the natural supply is small and the compound dissolves poorly in water, limiting how much reaches tumours in the body.
Covering studies from 2012 to 2025, the review explains the molecule's structure, how chemists build it in the laboratory, and how living systems produce it. Most attention goes to modified versions, especially changes at one end of the molecule that add new chemical groups. Those derivatives often killed cancer cells more strongly while keeping favourable behaviour.
Catalog record
| CREATOR | Qi-Hua Yu, Zhiyan Liu, Jiazheng Liu, Li-Ping Bai |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 63 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |