5-hydroxymethylcytosine signatures of tissue as potential predictive markers for platinum resistance in epithelial ovarian cancer patients
Yuan Xue, Zhanmiao Yi, Ping Yu, Cuiyu Huang, Hui Li, Mengzhu Zheng, Zhanqun Yang, Shengbo Xu, Hongyan Guo, Long Chen, Jian Lin, Libo Zhao · 2026
Read 5-hydroxymethylcytosine signatures of tissue as potential predictive markers for platinum resistance in epithelial ovarian cancer patients by Yuan Xue, Zhanmiao Yi, Ping Yu, Cuiyu Huang, Hui Li, Mengzhu Zheng, Zhanqun Yang, Shengbo Xu, Hongyan Guo, Long Chen, Jian Lin, Libo Zhao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13236981.txt.
Description
Platinum-based systemic therapy is the cornerstone of treatment for epithelial ovarian cancer (EOC). Although most patients initially respond to platinum-based therapy, they eventually develop drug resistance after multiple relapses. Currently, there is no effective method to predict platinum resistance in EOC patients. We collected EOC tissues from 50 patients, including 15 drug-resistant (DR) and 35 drug-sensitive (unDR) individuals.
Catalog record
| CREATOR | Yuan Xue, Zhanmiao Yi, Ping Yu, Cuiyu Huang, Hui Li, Mengzhu Zheng, Zhanqun Yang, Shengbo Xu, Hongyan Guo, Long Chen, Jian Lin, Libo Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |