Estradiol modulated brain connectivity in females during midlife performing an episodic memory task
Abigail A. Testo, Julie A. Dumas · 2026
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Description
Testo and Dumas study how the hormone estradiol shapes brain connections in women at midlife. Midlife brings a sharp hormonal shift for women, and falling estradiol may change how brain regions talk to each other. Such changes could help explain why memory and thinking differ so much between women of the same age.
The team scanned women's brains while they performed a memory task about past events. They linked connection patterns to estradiol, the main estrogen lost at menopause. Mapping this link could clarify who faces higher risk of unhealthy brain ageing, and whether hormone timing matters for protecting memory in the menopause years.
Catalog record
| CREATOR | Abigail A. Testo, Julie A. Dumas |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |