Connecting biospecimens and data: a scoping review-informed conceptual framework for digital infrastructure in biobanking and genomic research in low- and middle-income countries

Description

Anna Michalska-Falkowska and Karine Sargsyan reviewed in 2026 why biological samples and their digital data stay disconnected in poorer countries' biobanks. Samples are collected locally, yet the systems to store, link, and share their data often lag behind. That divide shuts local populations out of genomic medicine gains and invites extractive data practices by richer partners. More than one hundred fifty studies and policy papers informed their synthesis.

Four gaps underpin the divide in their analysis of the literature. Weak physical infrastructure, incompatible data systems, scarce staff with joint lab and data skills, and thin governance each play a role. Their proposed model, named DIGS, treats infrastructure, interoperability, governance, and skills as one cycle needing joint investment. Partnerships should centre local leadership over data decisions, the authors argue. Sustainability means growing local capability rather than only buying equipment.

Catalog record

Source: https://europepmc.org/articles/PMC13236664