LH supplementation in ovarian stimulation: propensity score and generalized estimating equations analysis over 2000 embryos
Merve Dizdar, Fazilet Kübra Boynukalın, Betül Dündar, Meral Gültomruk, İbrahim Kale, Zalihe Yarkıner, Mustafa Bahçeci, Nikolaos P. Polyzos, Gürkan Bozdağ · 2026
Read LH supplementation in ovarian stimulation: propensity score and generalized estimating equations analysis over 2000 embryos by Merve Dizdar, Fazilet Kübra Boynukalın, Betül Dündar, Meral Gültomruk, İbrahim Kale, Zalihe Yarkıner, Mustafa Bahçeci, Nikolaos P. Polyzos, Gürkan Bozdağ (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13236556.txt.
Description
Merve Dizdar and colleagues asked in 2026 whether adding a second fertility hormone during egg stimulation changes embryo chromosome health. Records covered thousands of IVF cycles with embryo genetic testing at one centre over six years. Nearly a thousand matched cycles were compared, half using one hormone alone and half with added LH activity. Matching balanced age and egg numbers between the compared groups.
Egg yield, maturity, and fertilization rates looked alike across the two stimulation styles. The share of embryos with a normal chromosome set was nearly identical between groups in the analysis. Older female age independently lowered the chance that an embryo was chromosomally normal. Good-looking embryos had roughly double the odds of being normal compared with poor-quality ones. Pregnancy, live birth, and miscarriage after transfer also showed no clear group differences.
Catalog record
| CREATOR | Merve Dizdar, Fazilet Kübra Boynukalın, Betül Dündar, Meral Gültomruk, İbrahim Kale, Zalihe Yarkıner, Mustafa Bahçeci, Nikolaos P. Polyzos, Gürkan Bozdağ |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |