Identification and characterization of lncRNA-stemness-immune regulatory patterns
Zhipeng Qian, Jiaqi Yin, Chunlong Zhang, Guohua Wang, Chunyu Wang, Yang Li, Yuming Zhao · 2026
Read Identification and characterization of lncRNA-stemness-immune regulatory patterns by Zhipeng Qian, Jiaqi Yin, Chunlong Zhang, Guohua Wang, Chunyu Wang, Yang Li, Yuming Zhao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13235729.txt.
Description
Zhipeng Qian and colleagues map a three-way conversation between long noncoding RNAs, stemness genes, and immunity across cancers. Cancer stem traits help tumors dodge the immune system and resist therapy. Their framework links each noncoding RNA to one stemness gene and one immune gene in a working triplet.
One triplet predicted survival across many cancers better than single genes alone. Triplets also forecast who would respond to immune checkpoint drugs in three patient groups. Adding mutation counts sharpened the forecasts. The work offers ready-made biomarker sets for matching patients to immunotherapy.
Catalog record
| CREATOR | Zhipeng Qian, Jiaqi Yin, Chunlong Zhang, Guohua Wang, Chunyu Wang, Yang Li, Yuming Zhao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |