Advanced azelaic acid hyalubilosome-loaded microneedles for potent anti-inflammatory, antioxidant, and antimicrobial for Acne treatment by up-regulation of Nrf2/HO-1 signaling pathway
Sammar Fathy Elhabal, Mohamed Fathi Mohamed Elrefai, Fatma E Hassan, Nahla Sameh Tolba, Rania Mostafa Abd El Galil, Suzan Awad AbdelGhany Morsy, Shady Allam, Amr M Emam, Hanaa Wanas, Marian Sobhy Azer, Mona Mohamed Ahmed, Hoda Ahmed Abdelmoneim, Marwa Fady, Ahmed Mohsen Elsaid Hamdan · 2026
Read Advanced azelaic acid hyalubilosome-loaded microneedles for potent anti-inflammatory, antioxidant, and antimicrobial for Acne treatment by up-regulation of Nrf2/HO-1 signaling pathway by Sammar Fathy Elhabal, Mohamed Fathi Mohamed Elrefai, Fatma E Hassan, Nahla Sameh Tolba, Rania Mostafa Abd El Galil, Suzan Awad AbdelGhany Morsy, Shady Allam, Amr M Emam, Hanaa Wanas, Marian Sobhy Azer, Mona Mohamed Ahmed, Hoda Ahmed Abdelmoneim, Marwa Fady, Ahmed Mohsen Elsaid Hamdan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13235371.txt.
Description
Sammar Fathy Elhabal leads a large team in 2026 in engineering a smarter acne treatment that carries an old drug through the skin barrier. Azelaic acid fights acne on several fronts, but it barely dissolves in water and hardly penetrates skin, so creams underperform.
The team packed the acid into tiny hybrid bubbles, part fat vesicle and part bile salt, then loaded those into dissolving microneedle patches that painlessly pierce the surface. The design was tuned with statistical software. In tests the system calmed inflammation, fought oxidation and bacteria, and switched on a protective cell pathway, a full package against a stubborn condition.
Catalog record
| CREATOR | Sammar Fathy Elhabal, Mohamed Fathi Mohamed Elrefai, Fatma E Hassan, Nahla Sameh Tolba, Rania Mostafa Abd El Galil, Suzan Awad AbdelGhany Morsy, Shady Allam, Amr M Emam, Hanaa Wanas, Marian Sobhy Azer, Mona Mohamed Ahmed, Hoda Ahmed Abdelmoneim, Marwa Fady, Ahmed Mohsen Elsaid Hamdan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 134 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |