Bulked segregant RNA sequencing and linkage mapping identify a Pm4 allele conferring stable powdery mildew resistance in wheat breeding line YZ16
Shiyu Zhuo, Wenping Gong, Xiaolu Wang, Linhong Gou, Jingjing He, Shihong Jiang, Cheng Liu, Hong Yang · 2026
Read Bulked segregant RNA sequencing and linkage mapping identify a Pm4 allele conferring stable powdery mildew resistance in wheat breeding line YZ16 by Shiyu Zhuo, Wenping Gong, Xiaolu Wang, Linhong Gou, Jingjing He, Shihong Jiang, Cheng Liu, Hong Yang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13235213.txt.
Description
Shiyu Zhuo and seven co-authors present a 2026 study pinning down the gene behind a wheat line's strong mildew resistance. Powdery mildew is a major wheat disease, and breeders need resistance genes with markers they can track. The line YZ16 resisted most tested strains of the fungus as a seedling and stayed resistant as an adult plant in the field. Crosses showed a single dominant gene was responsible.
Gene-hunting by pooled sequencing placed the gene at the tip of chromosome 2A. Fine mapping showed it travels perfectly with a marker for the known resistance gene Pm4. Sequencing proved the protein matches known Pm4 variants, so YZ16 carries that gene in a new source line. Two splice forms of the gene shifted after infection. Across two seasons the line's yield traits held up. The authors offer YZ16 as a donor for breeding, trackable by the marker.
Catalog record
| CREATOR | Shiyu Zhuo, Wenping Gong, Xiaolu Wang, Linhong Gou, Jingjing He, Shihong Jiang, Cheng Liu, Hong Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |