DPHD from Curcuma comosa Enhances the Expansion and Osteogenic Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells While Attenuating Senescence
Nittaya Boonmuen, Moe Moe Paing, Nareerat Sutjarit, Pakpoom Kheolamai, Sirikul Manochantr, Chairat Tantrawatpan, Waraluck Chaichompoo, Apichart Suksamrarn, Duangrat Tantikanlayaporn · 2026
Read DPHD from Curcuma comosa Enhances the Expansion and Osteogenic Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells While Attenuating Senescence by Nittaya Boonmuen, Moe Moe Paing, Nareerat Sutjarit, Pakpoom Kheolamai, Sirikul Manochantr, Chairat Tantrawatpan, Waraluck Chaichompoo, Apichart Suksamrarn, Duangrat Tantikanlayaporn (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13234631.txt.
Description
Nittaya Boonmuen and co-workers test a plant compound on human cord stem cells for bone regeneration, in a 2026 paper. Umbilical cord stem cells are promising for therapy, but they age out as they multiply in the lab. The compound, DPHD, comes from a turmeric relative long used in Thai medicine.
At low doses the compound raised cell growth while keeping stem cell identity markers intact. It lowered signs of cell ageing, cut the release of ageing-linked inflammatory signals, and reduced oxidative stress damage. Treated cells also formed bone more readily, with higher bone-building gene activity. The team links the effects to a known growth signaling path.
Catalog record
| CREATOR | Nittaya Boonmuen, Moe Moe Paing, Nareerat Sutjarit, Pakpoom Kheolamai, Sirikul Manochantr, Chairat Tantrawatpan, Waraluck Chaichompoo, Apichart Suksamrarn, Duangrat Tantikanlayaporn |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |