Hepatocyte estrogen-related receptor α modulates a gluconeogenic–epigenetic crosstalk counteracting MASLD/MASH progression
Jun Gao, Meng Yang, Rui Duan, Tongling Huang, Pengda Li, Lu Gao, Zhaocheng Lu, Chi-Wai Wong, Chang-An Geng, Min Guan · 2026
Read Hepatocyte estrogen-related receptor α modulates a gluconeogenic–epigenetic crosstalk counteracting MASLD/MASH progression by Jun Gao, Meng Yang, Rui Duan, Tongling Huang, Pengda Li, Lu Gao, Zhaocheng Lu, Chi-Wai Wong, Chang-An Geng, Min Guan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13233843.txt.
Description
Jun Gao and nine co-authors show a liver switch, ERR alpha, ties sugar make to gene tags gainst fat liver ill. Their study appeared in twenty twenty-six. Lactic waste is both a fuel and a tag donor in liver cells, yet its link to fat liver was not clear. The switch ran low in sick livers as waste and its tag form rose.
In mice, drill raised the switch and its mate, which steered waste to sugar make in place of tags. Loss of the switch made the ill worse; its boost in liver cells set tag piles right and curbed the ill. Age and laze are named as tune knobs.
Catalog record
| CREATOR | Jun Gao, Meng Yang, Rui Duan, Tongling Huang, Pengda Li, Lu Gao, Zhaocheng Lu, Chi-Wai Wong, Chang-An Geng, Min Guan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 88 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |