A tumor-resident Staphylococcus epidermidis strain exhibits genomic and metabolic traits driving hepatocellular carcinoma progression
Jinhua Yang, Yang Liu, Bowen Li, Tianqi Zhang, Liying Yan, Kunyu Zhang, Fangqi Xu, Zhiyue Wang, Ying Liu, Baiqiang Lin, Jianming Wang, Yunwei Wei · 2026
Read A tumor-resident Staphylococcus epidermidis strain exhibits genomic and metabolic traits driving hepatocellular carcinoma progression by Jinhua Yang, Yang Liu, Bowen Li, Tianqi Zhang, Liying Yan, Kunyu Zhang, Fangqi Xu, Zhiyue Wang, Ying Liu, Baiqiang Lin, Jianming Wang, Yunwei Wei (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13233812.txt.
Description
Jinhua Yang and colleagues published a 2026 study growing a living bacterium from inside liver tumors. Bacteria have been detected in hepatocellular carcinoma tissue, but the tiny amounts made it hard to grow strains and test whether they matter. With strict cleanliness controls and gene sequencing, the team found Staphylococcus enriched in late-stage tumors and cultured a Staphylococcus epidermidis strain they named GX3-2.
The strain sped up liver cancer cell growth and movement in dishes and was linked to faster tumor growth in a small mouse experiment where it was injected into tumors. Chemical profiling tied the bacterium to molecules including adenosine and 2-phenylethylamine, and to host gene programs for cell division and tissue invasion. The authors present the isolate as early proof that tumor-resident bacteria can shape cancer behavior.
Catalog record
| CREATOR | Jinhua Yang, Yang Liu, Bowen Li, Tianqi Zhang, Liying Yan, Kunyu Zhang, Fangqi Xu, Zhiyue Wang, Ying Liu, Baiqiang Lin, Jianming Wang, Yunwei Wei |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |