Longitudinal assessment and predictors of subjective taste change after hematopoietic cell transplantation (HCT)
Allan J Hovan, Michael T Brennan, Bengt Hasséus, Judith E Raber-Durlacher, Marie-Charlotte Huysmans, Alexa M G A Laheij, Stephanie J M van Leeuwen, Karin Garming Legert, Scott Isom, David M Kline, Nicole M A Blijlevens, Jan-Erik Johansson, Inger von Bültzingslöwen · 2026
Read Longitudinal assessment and predictors of subjective taste change after hematopoietic cell transplantation (HCT) by Allan J Hovan, Michael T Brennan, Bengt Hasséus, Judith E Raber-Durlacher, Marie-Charlotte Huysmans, Alexa M G A Laheij, Stephanie J M van Leeuwen, Karin Garming Legert, Scott Isom, David M Kline, Nicole M A Blijlevens, Jan-Erik Johansson, Inger von Bültzingslöwen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13233654.txt.
Description
Allan J Hovan and colleagues published a 2026 longitudinal study of taste change after hematopoietic cell transplantation, a stem cell treatment for blood cancers. Within the Orastem study, 238 patients at five cancer centers reported oral symptoms during hospitalization and for a year afterward. More than a third reported altered taste while in hospital, and over forty percent of those called it their most bothersome mouth symptom.
Three quarters of all patients reported at least some distress from taste change. Earlier chemotherapy and full-intensity conditioning predicted severe change during the hospital stay. Recipients of donor transplants fared worse at three months, and older age predicted severe change at six and twelve months. A small group, about thirteen percent, still felt distress at one year, marking a target for supportive care.
Catalog record
| CREATOR | Allan J Hovan, Michael T Brennan, Bengt Hasséus, Judith E Raber-Durlacher, Marie-Charlotte Huysmans, Alexa M G A Laheij, Stephanie J M van Leeuwen, Karin Garming Legert, Scott Isom, David M Kline, Nicole M A Blijlevens, Jan-Erik Johansson, Inger von Bültzingslöwen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |