Pathology-based thermal ablation safety margin for follicular adenoma: a digital whole-slide study of follicular carcinoma invasion
Yunfeng Qiao, Yun Niu, Zhenlong Zhao, Hanxiao Zhao, Yuton Liu, Ming-an Yu · 2026
Read Pathology-based thermal ablation safety margin for follicular adenoma: a digital whole-slide study of follicular carcinoma invasion by Yunfeng Qiao, Yun Niu, Zhenlong Zhao, Hanxiao Zhao, Yuton Liu, Ming-an Yu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13233275.txt.
Description
Yunfeng Qiao and colleagues published a 2026 pathology study measuring how far follicular thyroid cancer invades beyond its capsule. Benign follicular adenomas and these cancers look alike before surgery, so heat-based ablation of a supposed adenoma might undertreat a hidden cancer. The team reviewed digital slides from 43 surgically removed follicular cancers treated between 2016 and 2023.
Invasion past the capsule averaged about one and a half millimeters, while the hidden invasion that ultrasound cannot detect averaged roughly half a millimeter and never passed 1.36 millimeters in this group. Neither measure varied by tumor stage, cancer subtype, sex, or lymph node spread, though age related to wider capsule invasion. The measurements support ablating two millimeters beyond the visible tumor edge as a safety margin.
Catalog record
| CREATOR | Yunfeng Qiao, Yun Niu, Zhenlong Zhao, Hanxiao Zhao, Yuton Liu, Ming-an Yu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |