Epstein-Barr virus-associated multiple sclerosis: recent mechanistic advances and clinical therapeutic perspectives
Ruogu Cheng, Ye Gao, Ruoyi Zheng, Muzi Wen, Gaoling Li, Wenbin Pan, Yuqiao Liao, Linxin Wen, Yueyang Hu, Hannah Zhao-Fleming, Pei Shang · 2026
Read Epstein-Barr virus-associated multiple sclerosis: recent mechanistic advances and clinical therapeutic perspectives by Ruogu Cheng, Ye Gao, Ruoyi Zheng, Muzi Wen, Gaoling Li, Wenbin Pan, Yuqiao Liao, Linxin Wen, Yueyang Hu, Hannah Zhao-Fleming, Pei Shang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13233209.txt.
Description
Multiple sclerosis has long trailed a suspect: the Epstein-Barr virus, which infects most adults and then hides for life. Ruogu Cheng and co-authors review how the virus may set the disease off. When immunity dips, the virus can wake. Its proteins resemble some of the body's own, so immune attacks aimed at the virus may spill onto the brain's insulation.
The review details the misfires in T cells and B cells that follow infection. It also covers reactivation, the virus's second act, as a trigger for onset and relapse. Current drugs still fail to halt progression for many patients. The authors survey drug targets along the virus-disease chain, hoping for treatments that strike earlier causes.
Catalog record
| CREATOR | Ruogu Cheng, Ye Gao, Ruoyi Zheng, Muzi Wen, Gaoling Li, Wenbin Pan, Yuqiao Liao, Linxin Wen, Yueyang Hu, Hannah Zhao-Fleming, Pei Shang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |