Localized and sustained release of Botulinum Toxin A from supramolecular peptide hydrogel for strabismus treatment
Wei Guo, Hui Zhu, Yuchen Yao, Dan Huang, Tiantian Zhou, Xiaoqi Zhu, Jiaying Zhang, Gaolin Liang, Wenjun Zhan, Hu Liu · 2026
Read Localized and sustained release of Botulinum Toxin A from supramolecular peptide hydrogel for strabismus treatment by Wei Guo, Hui Zhu, Yuchen Yao, Dan Huang, Tiantian Zhou, Xiaoqi Zhu, Jiaying Zhang, Gaolin Liang, Wenjun Zhan, Hu Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13231837.txt.
Description
Wei Guo leads a team of ten authors in 2026 in building a gel that holds Botox exactly where an eye surgeon needs it. Botulinum toxin A treats crossed eyes without surgery, but the toxin drifts into nearby muscles, causing drooping lids, and its effect fades too soon.
The team co-assembled the toxin with a short peptide that self-organizes into a hydrogel under mild, body-like conditions. Locked inside, the toxin releases slowly and stays local instead of wandering. A depot like this could make a standard eye treatment both safer and longer lasting.
Catalog record
| CREATOR | Wei Guo, Hui Zhu, Yuchen Yao, Dan Huang, Tiantian Zhou, Xiaoqi Zhu, Jiaying Zhang, Gaolin Liang, Wenjun Zhan, Hu Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |