WGS reveals high-risk clones of Pseudomonas aeruginosa harbouring extensive antimicrobial and predicted anti-phage defense systems recovered from diabetic foot ulcer patients in Egypt
Mai A Amer, Manal M Darwish, Reham Monir, Ahmed Al Taweel, Ayat I Ghanem, Ihab N Hanna, Aya H Hefnawy, Nada S Gebreel, Noha M Soltan, Yara H Aboudewan, Samira M Hamed · 2026
Read WGS reveals high-risk clones of Pseudomonas aeruginosa harbouring extensive antimicrobial and predicted anti-phage defense systems recovered from diabetic foot ulcer patients in Egypt by Mai A Amer, Manal M Darwish, Reham Monir, Ahmed Al Taweel, Ayat I Ghanem, Ihab N Hanna, Aya H Hefnawy, Nada S Gebreel, Noha M Soltan, Yara H Aboudewan, Samira M Hamed (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13231603.txt.
Description
Mai A Amer and colleagues sequence in 2026 bacteria taken from diabetic foot ulcers in Egypt to map their resistance and defenses. Five isolates of Pseudomonas aeruginosa, a germ that thrives in chronic wounds, were tested against antibiotics and checked for slime layer growth. Every isolate resisted many drug classes, and two resisted nearly everything available.
Genomes fell into three line types, two of them known high-risk clones seen in hospitals worldwide. The clones carried mobile gene blocks with metal resistance plus a wide shield of systems that block virus attacks on bacteria. Up to thirty-two such anti-phage systems sat in one genome, which could blunt future virus-based treatments. Rich virulence gene sets completed a picture of hardy, hard-to-treat wound invaders.
Catalog record
| CREATOR | Mai A Amer, Manal M Darwish, Reham Monir, Ahmed Al Taweel, Ayat I Ghanem, Ihab N Hanna, Aya H Hefnawy, Nada S Gebreel, Noha M Soltan, Yara H Aboudewan, Samira M Hamed |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |