Ventilator Weaning Failure Induced by Oral Beraprost in a Patient after Femoral Endarterectomy: A Case Report

Masato Obayashi, Shoji Fukuda, Akinari Iwahori, Toru Iwahashi, Toshiki Fujiyoshi, Shun Suzuki, Masaki Kano, Ikki Kojima, Makoto Matsuda, Shinobu Akiyama, Yusuke Shimahara · 2026

Read Ventilator Weaning Failure Induced by Oral Beraprost in a Patient after Femoral Endarterectomy: A Case Report by Masato Obayashi, Shoji Fukuda, Akinari Iwahori, Toru Iwahashi, Toshiki Fujiyoshi, Shun Suzuki, Masaki Kano, Ikki Kojima, Makoto Matsuda, Shinobu Akiyama, Yusuke Shimahara (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13231185.txt.

Description

Masato Obayashi and colleagues report in 2026 a ninety-year-old man who could not come off a ventilator while taking a blood vessel drug. He received oral beraprost for severe leg artery disease after thigh artery surgery, on top of extensive lung collapse. Every attempt to wean him from the machine ended with fast breathing and dangerous drops in blood oxygen.

Stopping the drug ended the episodes, while restarting it brought the same collapse back, a pattern that ties the drug to the problem. Beraprost widens vessels everywhere, which can send blood into poorly aired lung zones and waste oxygen matching. Teams weaning fragile patients may want to review such vessel-widening drugs when progress stalls without a clear cause.

Catalog record

CREATORMasato Obayashi, Shoji Fukuda, Akinari Iwahori, Toru Iwahashi, Toshiki Fujiyoshi, Shun Suzuki, Masaki Kano, Ikki Kojima, Makoto Matsuda, Shinobu Akiyama, Yusuke Shimahara
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE17 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13231185

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