Host metabolic responses to SARS-CoV-2 and influenza viruses: parallels and contrasts
Charles Terra, Olivier Terrier, Audrey Le Gouellec · 2026
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Description
Charles Terra and colleagues review in 2026 how two major breathing viruses reshape the chemistry of the cells they infect. Both the coronavirus behind COVID-19 and influenza viruses hijack cell machinery to copy themselves. The review compares their effects on sugar use, energy cycles, and the building blocks for new virus parts.
Shared changes include faster sugar breakdown without oxygen, loss of key amino acids, and shifts in pathways tied to inflammation. Each virus also leaves its own pattern, with different effects on sugar stores and on the late steps of the energy cycle. Specific viral proteins drive many of these shifts, and some track with worse illness. Knowing the patterns could point to new tests and treatments.
Catalog record
| CREATOR | Charles Terra, Olivier Terrier, Audrey Le Gouellec |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |