Bridging the scales for deformable red blood cells simulation: from resolved immersed boundary to unresolved CFD–DEM
Carmine Porcaro, Jonas Latt, Mahdi Saeedipour · 2026
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Description
Carmine Porcaro and colleagues present in 2026 a way to simulate blood flow with red cells at a much larger scale. Detailed models that track each flexible cell are accurate but too slow for big vessels or devices. Treating blood as a simple fluid is fast, yet it misses effects that come from the cells themselves.
The team first ran detailed cell simulations to record how cells deform and what drag and lift they feel. Those records trained simpler rules for a faster solver that treats cells without drawing each membrane. The faster solver can handle hundreds of thousands of cells at far lower cost. Tests covered plasma separation devices and narrowed channels that mimic blocked veins.
Catalog record
| CREATOR | Carmine Porcaro, Jonas Latt, Mahdi Saeedipour |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |