Ticagrelor Versus Clopidogrel in Patients With ST-Elevation Myocardial Infarction and Elevated Platelet Counts: A Multicenter Comparative Analysis of Ischemic Outcomes
Fang-Jie Ji, Xian Shao, Tian-Shu Gu, Yu-Kun Zhang, Su-Tao Hu, Chao Jiang, Jing-Kun Zhang, Xue Wu, Seung-Woon Rha, Xing Liu, Tong Liu, Kang-Yin Chen · 2026
Read Ticagrelor Versus Clopidogrel in Patients With ST-Elevation Myocardial Infarction and Elevated Platelet Counts: A Multicenter Comparative Analysis of Ischemic Outcomes by Fang-Jie Ji, Xian Shao, Tian-Shu Gu, Yu-Kun Zhang, Su-Tao Hu, Chao Jiang, Jing-Kun Zhang, Xue Wu, Seung-Woon Rha, Xing Liu, Tong Liu, Kang-Yin Chen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13227351.txt.
Description
Fang-Jie Ji and co-authors compared, in a 2026 study, two blood-thinning drugs after severe heart attacks in patients with high platelet counts. Dual antiplatelet therapy is standard after a STEMI heart attack, but which partner drug suits patients whose platelet counts run high was unclear. Records came from 82 hospitals in Tianjin spanning 2010 to 2023.
Matching balanced the groups at 461 patients split between ticagrelor and clopidogrel. The ticagrelor group suffered significantly fewer major cardiac and brain events, the study's main outcome. Deaths, repeat heart attacks, reoperations, strokes, and serious bleeds were also tallied. The authors read the edge as real for this high-platelet group, while noting the data are records, not a randomized trial. A head-to-head trial could test the signal.
Catalog record
| CREATOR | Fang-Jie Ji, Xian Shao, Tian-Shu Gu, Yu-Kun Zhang, Su-Tao Hu, Chao Jiang, Jing-Kun Zhang, Xue Wu, Seung-Woon Rha, Xing Liu, Tong Liu, Kang-Yin Chen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |