Evaluating place cell detection methods in Rats and Humans: Implications for cross-species spatial coding
Weijia Zhang, Thomas Donoghue, Salman E. Qasim, Joshua Jacobs, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush · 2026
Read Evaluating place cell detection methods in Rats and Humans: Implications for cross-species spatial coding by Weijia Zhang, Thomas Donoghue, Salman E. Qasim, Joshua Jacobs, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13225663.txt.
Description
Weijia Zhang and co-authors compare a 2026 methods study of place cells, the hippocampal neurons that fire only when an animal sits in a particular spot. Rodent laboratories usually detect them with a spatial-information measure plus stability checks, while human studies favour a different statistical test. Whether the two styles find the same cells matters for translating decades of rat work to people.
Applying several detection pipelines to rat and human recordings, backed by simulations, the team found the methods respond to different features. One reflects how sharply peak firing stands out, the other how consistent firing stays across trials. Rat samples included a strongly tuned population that human samples lacked, with human cells clustering at the weaker end.
Catalog record
| CREATOR | Weijia Zhang, Thomas Donoghue, Salman E. Qasim, Joshua Jacobs, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush, Hugues Berry, Daniel Bush |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 125 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |