Identification and validation of autophagy-related genes in keratoconus and their correlation with immune infiltration
Sutong Li, Gang Wang, Jing Chen, Naiyang Li · 2026
Read Identification and validation of autophagy-related genes in keratoconus and their correlation with immune infiltration by Sutong Li, Gang Wang, Jing Chen, Naiyang Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13225602.txt.
Description
Sutong Li and co-authors hunt for self-eating genes tied to a cone-shaped cornea disease, in work published in 2026. The disease, keratoconus, thins the cornea on both sides in uneven ways. Self-eating, or autophagy, keeps cells sound under stress, but its gene marks in this disease were unclear. The team mined two public gene data sets from patients.
Fourteen such genes split patients from healthy peers. Nine hub genes survived a learning-model screen, and most tied to stress and death pathways. Immune cell mixes also shifted with the disease. Lab checks confirmed eight of the nine genes ran low in patient tissue. The work maps fresh leads for study.
Catalog record
| CREATOR | Sutong Li, Gang Wang, Jing Chen, Naiyang Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |