AQP4+ NMOSD, MDA5+ Clinically Amyopathic Dermatomyositis and sHLH in a Pediatric Patient: A Case Report and Literature Review
Zhanwei Zhang, Zhangqian Xiao, Fang He, Fei Yin, Jing Peng, Xiaolu Deng · 2026
Read AQP4+ NMOSD, MDA5+ Clinically Amyopathic Dermatomyositis and sHLH in a Pediatric Patient: A Case Report and Literature Review by Zhanwei Zhang, Zhangqian Xiao, Fang He, Fei Yin, Jing Peng, Xiaolu Deng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13222851.txt.
Description
Zhanwei Zhang and co-authors describe a child carrying three overlapping autoimmune conditions at once, in a 2026 case report with literature review. An 8-year-old girl arrived with fever, headache, confusion, vomiting, blurred vision, rash, urinary difficulty, and neck and back pain. Testing pointed to neuromyelitis optica spectrum disorder, a muscle disease called clinically amyopathic dermatomyositis, and secondary HLH, an immune overactivation syndrome.
Aggressive immune treatment followed, combining steroids, immunoglobulin, rituximab, and tacrolimus. She recovered fully and stayed relapse-free at last follow-up. The authors note type I interferon as a possible shared link between the nerve and muscle diseases, and they advise watching for skin signs in children with the nerve disorder.
Catalog record
| CREATOR | Zhanwei Zhang, Zhangqian Xiao, Fang He, Fei Yin, Jing Peng, Xiaolu Deng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |