Methods for Analyzing RNA Pseudoknots via Chord Diagrams and Intersection Graphs

Rayan Ibrahim, Allison H. Moore · 2026

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Description

Rayan Ibrahim and Allison H. Moore present a 2026 math method for analyzing pseudoknots, the tangled folds that form in RNA molecules. Counting and sorting these structures with rigor has resisted standard approaches. Their scheme turns an RNA diagram into a graph, then applies a distance measure to that graph's crossings.

A pseudoknot is defined formally through a weighted covering problem on the graph. The resulting method, built in MATLAB, enumerates them and sorts RNA structures while sensing 3D shape features. Tests on a public database confirmed genus as a robust gauge of knot complexity. The work gives RNA modelers firmer math footing.

Catalog record

CREATORRayan Ibrahim, Allison H. Moore
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE170 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13221419

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