Prevalence and associated factors of subjective cognitive decline (SCD Plus): a cross-sectional analysis of three population-based European cohorts

Andrea E. Zülke, Melanie Luppa, Christian Sander, Ronny Baber, Ronald Biemann, Kerstin Wirkner, Samira Zeynalova, Silke Zachariae, Milica Matijevic, Christoph Engel, Nigar Reyes, Andreas Hinz, Heide Glaesmer, Matthias L. Schroeter, A. Veronica Witte, Arno Villringer, Markus Löffler, Carol Brayne, St · 2026

Read Prevalence and associated factors of subjective cognitive decline (SCD Plus): a cross-sectional analysis of three population-based European cohorts by Andrea E. Zülke, Melanie Luppa, Christian Sander, Ronny Baber, Ronald Biemann, Kerstin Wirkner, Samira Zeynalova, Silke Zachariae, Milica Matijevic, Christoph Engel, Nigar Reyes, Andreas Hinz, Heide Glaesmer, Matthias L. Schroeter, A. Veronica Witte, Arno Villringer, Markus Löffler, Carol Brayne, St (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13220450.txt.

Description

Andrea Zülke and co-authors measure how common early memory complaints are in older Europeans, in a 2026 study. People who feel their memory slipping, while tests stay normal, may face higher Alzheimer's risk. A stricter label, SCD Plus, adds features like worry and recent onset to sharpen that signal.

Three population cohorts from Germany and England supplied 18,795 adults aged 60 and up. By a shared definition, 37.9 percent met SCD Plus, though rates ranged widely by cohort. The label linked to higher education, low mood, anxiety, and several long-term diseases. It linked less often to some other traits in the pooled data. The study gives planners a firm count for a group that prevention trials may want to reach.

Catalog record

CREATORAndrea E. Zülke, Melanie Luppa, Christian Sander, Ronny Baber, Ronald Biemann, Kerstin Wirkner, Samira Zeynalova, Silke Zachariae, Milica Matijevic, Christoph Engel, Nigar Reyes, Andreas Hinz, Heide Glaesmer, Matthias L. Schroeter, A. Veronica Witte, Arno Villringer, Markus Löffler, Carol Brayne, St
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE63 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13220450

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