Liquid-Liquid Phase Separation in Cancer Drug Resistance: Mechanisms and Therapeutic Opportunities

Yiyang Zhao, Changchang Sun, Qihan Dong, Jiangyang He, Yan Wang, Ling Bi · 2026

Read Liquid-Liquid Phase Separation in Cancer Drug Resistance: Mechanisms and Therapeutic Opportunities by Yiyang Zhao, Changchang Sun, Qihan Dong, Jiangyang He, Yan Wang, Ling Bi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13220088.txt.

Description

Yiyang Zhao and co-authors review how drip-like blobs inside cancer cells help tumors shrug off drugs. Cells sort their parts in part through such blobs, which form with no skin when thick soups split. Their 2026 review pulls proof that skewed blob work props up drug grit in many ways. Blobs can keep growth scripts on past drug hits and wall drugs out of reach.

Shields span immune marks, DNA fix, stem-like grit, and flash care grit. Cell cycle and frame shifts join the web. Gene-wide and fine lab tools that track blob dance get a scan. The last part weighs drug plans that aim at the blobs. Such plans could crack grit that plain drugs leave whole.

Catalog record

CREATORYiyang Zhao, Changchang Sun, Qihan Dong, Jiangyang He, Yan Wang, Ling Bi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE63 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13220088

Browse the full library · About the Tower of Babel