Anti-diabetic retinopathy molecular mechanism of Dihuang Yinzi: insights from network pharmacology, metabolomics, and microbiome analysis
Jinmiao Chai, Wanwei Gui, Junlong Zhang, Wenbin He, Qinqing Li · 2026
Read Anti-diabetic retinopathy molecular mechanism of Dihuang Yinzi: insights from network pharmacology, metabolomics, and microbiome analysis by Jinmiao Chai, Wanwei Gui, Junlong Zhang, Wenbin He, Qinqing Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13219277.txt.
Description
Jinmiao Chai and co-authors probe a classic herbal formula in a 2026 study of diabetic eye disease. Diabetic retinopathy damages small eye vessels and springs from genes, metabolism, and microbes acting together. The formula, Dihuang Yinzi, shows promise against the disease, yet its workings stay vague. The team combined network analysis, chemical profiling, and gut microbe study in a mouse model.
Eighteen mice split into healthy, diseased, and treated groups for the tests. The combined lens hunted the genes, compounds, and microbial species that carry the formula's effect. Naming those players turns a broad traditional claim into targets that later trials can check. The approach also shows how multi lens methods can crack open other herbal formulas.
Catalog record
| CREATOR | Jinmiao Chai, Wanwei Gui, Junlong Zhang, Wenbin He, Qinqing Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |