Factors associated with acquired hypothalamic obesity in children with hypothalamic tumors: a comparative single-center study
Fulya METE KALAYCI, Deniz ÖZALP KIZILAY, Eda ATASEVEN, Mehmet KANTAR, Uluç ÖZKIZILTAN, Elif BOLAT, Aslı SUNER KARAKÜLAH, Damla GÖKŞEN, Şükran DARCAN, Samim ÖZEN · 2026
Read Factors associated with acquired hypothalamic obesity in children with hypothalamic tumors: a comparative single-center study by Fulya METE KALAYCI, Deniz ÖZALP KIZILAY, Eda ATASEVEN, Mehmet KANTAR, Uluç ÖZKIZILTAN, Elif BOLAT, Aslı SUNER KARAKÜLAH, Damla GÖKŞEN, Şükran DARCAN, Samim ÖZEN (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13219077.txt.
Description
Fulya Mete Kalayci and colleagues examine which children with hypothalamic tumors go on to develop obesity in a 2026 study. Damage to the hypothalamus, the brain's appetite and hormone centre, can trigger rapid weight gain, but not every child with a tumor there becomes obese. Knowing which features travel with the outcome could focus prevention.
The study covered thirty-four children followed between 1999 and 2020, most often with optic glioma, pilocytic astrocytoma, or craniopharyngioma. Fifteen children, about forty-four percent, became obese, typically within three months of diagnosis. At diagnosis, obesity was linked to having had a skull-opening operation and to adrenal insufficiency and underactive sex hormone production. Once the analysis adjusted, surgical approach no longer predicted obesity, a caution the authors state. Insulin resistance and abnormal blood lipids clustered in the obese group. The study underlines how fast the weight gain arrives and how entangled it is with hormone deficits.
Catalog record
| CREATOR | Fulya METE KALAYCI, Deniz ÖZALP KIZILAY, Eda ATASEVEN, Mehmet KANTAR, Uluç ÖZKIZILTAN, Elif BOLAT, Aslı SUNER KARAKÜLAH, Damla GÖKŞEN, Şükran DARCAN, Samim ÖZEN |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |