Advances in vulvovaginal candidiasis research: a comprehensive review from epidemiology, diagnosis, treatment to resistance mechanisms

Weipei Zhu, Liangsheng Guo · 2026

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Description

Weipei Zhu and Liangsheng Guo bring vulvovaginal candidiasis research up to date, from who gets it to why drugs fail. The common yeast infection is getting harder to treat as non-albicans species spread, azole resistance climbs, and biofilms shield the fungus. Their review ranges across epidemiology, diagnostics, therapies, and resistance machinery.

The resistance playbook includes biofilm growth, drug-pumping overexpression, target mutations, and rewired regulators. The authors push three practical shifts. Use molecular identification routinely instead of guesswork. Read susceptibility testing with vaginal acidity in mind. Reach for non-azole options like boric acid and the two newly approved agents when resistance looms. Biofilm breakers, probiotics, and nano-delivery round out the coming toolkit for recurrent disease.

Catalog record

CREATORWeipei Zhu, Liangsheng Guo
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE66 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13218972

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