Gut microbiota responses to bariatric surgery are associated with metabolic outcomes and type 2 diabetes remission
Lisa M. Olsson, Heidi Borgeraas, Rima M. Chakaroun, Dag Hofsø, Jens Kristoffer Hertel, Chinmay Dwibedi, Matthias Mitteregger, Jens Juul Holst, Valentina Tremaroli, Jøran Hjelmesæth, Fredrik Bäckhed · 2026
Read Gut microbiota responses to bariatric surgery are associated with metabolic outcomes and type 2 diabetes remission by Lisa M. Olsson, Heidi Borgeraas, Rima M. Chakaroun, Dag Hofsø, Jens Kristoffer Hertel, Chinmay Dwibedi, Matthias Mitteregger, Jens Juul Holst, Valentina Tremaroli, Jøran Hjelmesæth, Fredrik Bäckhed (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13218940.txt.
Description
Lisa Olsson and co-authors published a 2026 study on how gut microbes shift after weight-loss surgery, and whether those shifts track diabetes remission. Two operations, gastric bypass and sleeve gastrectomy, both improve obesity and type 2 diabetes. Both also reshape the gut microbiome. Whether the microbes help cause the remission, or merely witness it, was unclear.
The work is a subanalysis of a randomized trial comparing the two operations. Thirty-nine bypass and thirty-eight sleeve patients with obesity and diabetes gave stool samples before surgery and twelve months after. Both operations altered the fecal microbiome. The team linked the patterns of change to metabolic outcomes, including who achieved remission. Such links matter because a microbial signature of success could become a target: if certain shifts accompany remission, therapies might aim to reproduce them without surgery. The study adds controlled, head-to-head data to a hype-prone field.
Catalog record
| CREATOR | Lisa M. Olsson, Heidi Borgeraas, Rima M. Chakaroun, Dag Hofsø, Jens Kristoffer Hertel, Chinmay Dwibedi, Matthias Mitteregger, Jens Juul Holst, Valentina Tremaroli, Jøran Hjelmesæth, Fredrik Bäckhed |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 78 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |