Immature platelets: A useful tool for thrombocytopenia etiology classification in adults

Raphael Ferreira Pimentel, Tayná Regina Leal dos Santos, Marcos André Cavalcanti Bezerra, Betânia Lucena Domingues Hatzlhofer, Maria Tereza Cartaxo Muniz · 2026

Read Immature platelets: A useful tool for thrombocytopenia etiology classification in adults by Raphael Ferreira Pimentel, Tayná Regina Leal dos Santos, Marcos André Cavalcanti Bezerra, Betânia Lucena Domingues Hatzlhofer, Maria Tereza Cartaxo Muniz (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13217495.txt.

Description

Raphael Ferreira Pimentel and co-authors present a 2026 laboratory study of immature platelets as a shortcut for diagnosing why a patient's platelet count is low. The two great causes, platelets being destroyed in circulation or the marrow failing to make them, demand opposite treatments, and marrow biopsy is the slow way to tell them apart.

The study measured 444 people: healthy donors, patients with destructive causes such as immune thrombocytopenia, and patients with marrow failure from aplastic anaemia, chemotherapy, leukaemia, or myeloma. The immature platelet fraction ran highest in the destruction group, with a median of 16.5 percent, against 5.0 percent in marrow failure. A cut-off of 8.3 percent separated the groups well. The authors recommend adding this cheap, one-minute automated measure to routine workups.

Catalog record

CREATORRaphael Ferreira Pimentel, Tayná Regina Leal dos Santos, Marcos André Cavalcanti Bezerra, Betânia Lucena Domingues Hatzlhofer, Maria Tereza Cartaxo Muniz
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13217495

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