Linkage of kynurenine pathway metabolites to neuroinflammation in drug-naive children with attention-deficit/hyperactivity disorder: A cross-sectional, case–control study

Kübranur Ünal, Yasemin Taş Torun, Mehmet Emre Erol, Cansu Özbaş, Zeynep Kübra Kurt · 2026

Read Linkage of kynurenine pathway metabolites to neuroinflammation in drug-naive children with attention-deficit/hyperactivity disorder: A cross-sectional, case–control study by Kübranur Ünal, Yasemin Taş Torun, Mehmet Emre Erol, Cansu Özbaş, Zeynep Kübra Kurt (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13217210.txt.

Description

Ünal and colleagues test whether a chemical pathway in the blood tracks brain inflammation in children with ADHD. Attention-deficit and hyperactivity disorder affects school, social, and family life, yet its biology stays partly unclear. The team measured kynurenine pathway products, which are made when the body processes tryptophan, in children never yet treated with ADHD drugs.

Blood came from 51 such children and 36 healthy peers of similar age and sex. Comparing the products and their ratios let the team probe links between immune activity and the disorder. If certain patterns hold up, they could point to inflammation's role in ADHD and, one day, to blood markers that support diagnosis.

Catalog record

CREATORKübranur Ünal, Yasemin Taş Torun, Mehmet Emre Erol, Cansu Özbaş, Zeynep Kübra Kurt
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13217210

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