Annulus fracture underlies radiation-induced sperm dysfunction revealed by multimodal nano-imaging
Nuo Chen, Hongyu Chen, Jingcheng Xiao, Bo He, Difei Zhang, Xinye Yuan, Pingping Wen, Huaidong Jiang · 2026
Read Annulus fracture underlies radiation-induced sperm dysfunction revealed by multimodal nano-imaging by Nuo Chen, Hongyu Chen, Jingcheng Xiao, Bo He, Difei Zhang, Xinye Yuan, Pingping Wen, Huaidong Jiang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13216213.txt.
Description
Nuo Chen and co-authors present a 2026 imaging study pinpointing where radiation physically breaks mouse sperm. Radiation is known to cut sperm counts and movement, but the damaged structures had stayed blurry at the nanoscale.
The team combined four imaging methods, including synchrotron X-ray techniques that view sperm close to their natural state. After a single radiation dose, the clearest injury was fracture of the annulus. That ring joins the sperm's midpiece to its tail, and it was damaged together with the fibrous sheath that stiffens the tail. A sheath protein called AKAP4 dropped in step with the damage. The authors offer the platform as a general way to inspect nanoscale injury in complex cells.
Catalog record
| CREATOR | Nuo Chen, Hongyu Chen, Jingcheng Xiao, Bo He, Difei Zhang, Xinye Yuan, Pingping Wen, Huaidong Jiang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |