Noncardiogenic Pulmonary Edema After Neostigmine Administration During Emergence From General Anesthesia: A Case Report
Jean-Claude Stephan, Mikhael Kossaify, Souheil Chamandi, Anthony Kanbar, Shashank Kaushik · 2026
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Description
Jean-Claude Stephan and co-authors report a 2026 case of sudden lung flooding after a routine anaesthetic reversal drug. A healthy 27-year-old man developed noncardiogenic pulmonary edema minutes after receiving neostigmine with atropine at the end of an appendectomy.
Before the breathing tube could be removed, his oxygen levels crashed, airway pressures spiked, and pink frothy fluid filled the tube, with chest imaging showing diffuse infiltrates in both lungs. Heart failure, fluid overload, suction injury, and allergy were each weighed and set aside using bedside ultrasound, the small fluid volume given, and normal allergy blood tests plus negative skin testing. He recovered fully after intensive care and was extubated twelve hours later. The authors present the link to neostigmine as a diagnosis of exclusion.
Catalog record
| CREATOR | Jean-Claude Stephan, Mikhael Kossaify, Souheil Chamandi, Anthony Kanbar, Shashank Kaushik |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 14 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |