Molecular diagnostics for cutaneous leishmaniasis: progress towards fulfilling the WHO target product profile
Jan Jarzabek, Paul William Denny · 2026
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Description
Jarzabek and Denny reviewed tests for cutaneous leishmaniasis in twenty twenty-five, a skin disease caused by a parasite spread by sand flies. The World Health Organization has set target goals for a better test: more accurate and cheaper than current tools. Knowing the exact species matters more now as drug resistance grows.
Blood tests cannot identify the species, while gene tests need costly machines. Heat-based gene tests called LAMP are promising, but few are species-specific so far, and Ethiopia is neglected in this work. Cheap devices built during the COVID-19 pandemic await testing for this disease. Image analysis by AI offers another route. The authors map both the chances and the hurdles ahead.
Catalog record
| CREATOR | Jan Jarzabek, Paul William Denny |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |