Rapid Microbiological Diagnostics for Sepsis: Narrative Review of Current and Prospective Approaches

Luke B. Harrison, Zahra N. Sohani, David Lasry, Mathew P. Cheng, Todd C. Lee, Ahmed Babiker, Sameer S. Kadri, Alexander Lawandi · 2026

Read Rapid Microbiological Diagnostics for Sepsis: Narrative Review of Current and Prospective Approaches by Luke B. Harrison, Zahra N. Sohani, David Lasry, Mathew P. Cheng, Todd C. Lee, Ahmed Babiker, Sameer S. Kadri, Alexander Lawandi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13215682.txt.

Description

Luke B. Harrison and co-authors present a 2026 narrative review of rapid laboratory tests for sepsis, written as a primer for critical care clinicians. Finding the causative microbe quickly matters because early, well-matched antibiotics save lives.

The review sorts tools into three families. Some speed up work on positive blood cultures, still the standard test. Others detect microbial DNA directly in patient samples, and a third group detects antigens instead. Direct methods can return answers within hours but trade off sensitivity, specificity, and ease of interpretation in different ways. The authors stress that availability and performance vary widely, so choosing tools is a joint decision with the microbiology laboratory.

Catalog record

CREATORLuke B. Harrison, Zahra N. Sohani, David Lasry, Mathew P. Cheng, Todd C. Lee, Ahmed Babiker, Sameer S. Kadri, Alexander Lawandi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13215682

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