Fibromyalgia and Risk of Alzheimer’s DiseaseRelated Dementia: A Nationwide Bidirectional Case–Control Study
Eli Magen, Israel Magen, Eugene Merzon, Ilan Green, Avivit Golan-Cohen, Shlomo Vinker, Ariel Israel · 2026
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Description
Eli Magen and co-authors ask whether fibromyalgia and Alzheimer's-type dementia travel together, and in which direction. They ran a nationwide case-control study in Israel with more than nine thousand fibromyalgia patients and forty-six thousand matched controls. Looking twenty years before the pain diagnosis and ten years after let them test the order of events.
Before diagnosis, dementia was no more common in the fibromyalgia group, and the Alzheimer's form was actually less common. After diagnosis, the picture flipped: Alzheimer's-type dementia appeared more often in patients than in controls over the following decade. Other dementia forms showed no consistent link, though cases were few. The authors read the pattern as a possible late rise in risk after fibromyalgia appears. They caution that the design shows association, not proof of cause.
Catalog record
| CREATOR | Eli Magen, Israel Magen, Eugene Merzon, Ilan Green, Avivit Golan-Cohen, Shlomo Vinker, Ariel Israel |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |