Non-invasive in vivo monitoring of transplanted human intestinal organoids using bioluminescence
Chioma Moneme, Antonio Vinicios Alves da Silva, Prisca C. Obidike, Bryan A. Hogg, Georgia B. Brousseau, Casandra Robinson, Christian Roig-Laboy, José Kleybson de Sousa, Yuwen Zhang, Lily S. Cheng, Sean R. Moore · 2026
Read Non-invasive in vivo monitoring of transplanted human intestinal organoids using bioluminescence by Chioma Moneme, Antonio Vinicios Alves da Silva, Prisca C. Obidike, Bryan A. Hogg, Georgia B. Brousseau, Casandra Robinson, Christian Roig-Laboy, José Kleybson de Sousa, Yuwen Zhang, Lily S. Cheng, Sean R. Moore (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13214524.txt.
Description
Chioma Moneme and a team of co-authors built a glowing tracker for lab grown gut tissue in a 2026 paper. The tissue, grown from human stem cells, mimics the early small gut. Planting it in animals lets labs watch it grow, but checks used to mean killing the animal and cutting the graft out.
They gave the gut cells a red shifted glow gene that did not harm their growth. Grafts went under the kidney skin of ten mice with weak immune systems. Weekly glow scans picked up nine of ten grafts by week two, and the glow grew over twelve weeks. Glow strength matched graft weight at the end with a near perfect fit. The tool lets one animal be tracked over time.
Catalog record
| CREATOR | Chioma Moneme, Antonio Vinicios Alves da Silva, Prisca C. Obidike, Bryan A. Hogg, Georgia B. Brousseau, Casandra Robinson, Christian Roig-Laboy, José Kleybson de Sousa, Yuwen Zhang, Lily S. Cheng, Sean R. Moore |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |