Alveolar dysregulation of host response in pneumonia and ARDS: implications for immune modulation and infection

LS Boers, L Maessen, J Wauters, ED Morrell, A Sarma, A Conway Morris, LDJ Bos · 2026

Read Alveolar dysregulation of host response in pneumonia and ARDS: implications for immune modulation and infection by LS Boers, L Maessen, J Wauters, ED Morrell, A Sarma, A Conway Morris, LDJ Bos (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13214341.txt.

Description

L. S. Boers and colleagues review in 2026 how the lung's air sacs mishandle immune defence in pneumonia and in acute respiratory distress syndrome. Blood tests miss much of this local story, yet events inside the air sacs decide clearance, injury, and recovery.

Across community, hospital, and ventilator-linked pneumonias, germs often die quickly while local inflammation burns on, fed by injured lining cells, neutrophils, and faltering macrophages. Ventilation itself can weaken defences and invite new infection. Patients diverge toward stubborn over-inflammation or immune exhaustion, steering them toward healing or scarring. Weakened local defences also let dormant viruses wake and fungi invade, prolonging ventilation.

Catalog record

CREATORLS Boers, L Maessen, J Wauters, ED Morrell, A Sarma, A Conway Morris, LDJ Bos
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13214341

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