Delayed transcallosal conduction to the lesioned sensorimotor cortex in multiple Sclerosis: A combined TMS 7 T-MRI study
Mads A.J. Madsen, Lasse Christiansen, Vanessa Wiggermann, Henrik Lundell, Jeppe Romme Christensen, Morten Blinkenberg, Finn Sellebjerg, Hartwig R. Siebner · 2026
Read Delayed transcallosal conduction to the lesioned sensorimotor cortex in multiple Sclerosis: A combined TMS 7 T-MRI study by Mads A.J. Madsen, Lasse Christiansen, Vanessa Wiggermann, Henrik Lundell, Jeppe Romme Christensen, Morten Blinkenberg, Finn Sellebjerg, Hartwig R. Siebner (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13214299.txt.
Description
Mads Madsen and co-authors measure slowed brain signals across hemispheres in multiple sclerosis in a 2026 study. Thirty-eight patients and twenty controls got ultra high field scans and magnetic brain pulses. Lesions in the hand movement area were mapped per hemisphere. Pulse timing gauged how fast inhibition crosses between the two sides.
Crossing time ran long in patients versus controls. Signals heading into a lesioned side slowed most, in a one way pattern. That delay tied to a lesion type inside the cortex itself. Fiber microstructure measures did not explain the delay. Cortex damage, not just wire damage, slows cross talk in this disease.
Catalog record
| CREATOR | Mads A.J. Madsen, Lasse Christiansen, Vanessa Wiggermann, Henrik Lundell, Jeppe Romme Christensen, Morten Blinkenberg, Finn Sellebjerg, Hartwig R. Siebner |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |