Transient Hyperprolactinemia Associated With Semaglutide in a Patient With Hashimoto’s Thyroiditis

Gabriela N F Guimarães, Semonti Nandi · 2026

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Description

Gabriela N. F. Guimarães and Semonti Nandi report in 2026 a woman whose prolactin hormone rose sharply while she took the weight-loss and diabetes drug semaglutide, then settled once she stopped. She also lived with a well-controlled underactive thyroid condition.

Her prolactin approached a level that often triggers a search for a pituitary tumour, yet she had no symptoms and a scan showed no growth. No other treatment was needed, because levels normalised after the drug ended. The authors suggest the drug class may nudge prolactin control through brain pathways in susceptible people. Clinicians, they advise, should consider medicines before assuming a tumour explains a high reading.

Catalog record

CREATORGabriela N F Guimarães, Semonti Nandi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE18 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13213196

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