Sex-Related Differences in Circular RNA Expression in Multiple Sclerosis: A Pilot Study
Valeria Lodde, Ignazio Roberto Zarbo, Gabriele Farina, Enrico Zoroddu, Paolo Solla, Giuseppe Delogu, Myriam Gorospe, Matteo Floris, Ilaria Campesi, Maria Laura Idda · 2026
Read Sex-Related Differences in Circular RNA Expression in Multiple Sclerosis: A Pilot Study by Valeria Lodde, Ignazio Roberto Zarbo, Gabriele Farina, Enrico Zoroddu, Paolo Solla, Giuseppe Delogu, Myriam Gorospe, Matteo Floris, Ilaria Campesi, Maria Laura Idda (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13212822.txt.
Description
Valeria Lodde leads a 2026 pilot study on circular RNA molecules in multiple sclerosis, asking whether their levels differ between women and men. The disease strikes women far more often, and these stable ring-shaped RNAs help regulate immune and nerve cells.
Reanalysis of an earlier dataset found 33 circular RNAs differing between female and male patients in blood immune cells. A fresh small cohort confirmed five of them, including one that ran higher in patients with greater disability and progressive disease. Treatment exposure also seemed to influence levels. The authors stress that larger studies must untangle sex, severity, and therapy effects before any clinical use.
Catalog record
| CREATOR | Valeria Lodde, Ignazio Roberto Zarbo, Gabriele Farina, Enrico Zoroddu, Paolo Solla, Giuseppe Delogu, Myriam Gorospe, Matteo Floris, Ilaria Campesi, Maria Laura Idda |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |