The Sanctuary Within: Development of CD20+ CNS Lymphoma Despite Peripheral B‐Cell Depletion by Rituximab in a Multiple Sclerosis Patient

Mohammad Hossein Harirchian, Seyed Ehsan Mohammadianinejad, Asghar Bayati, Vahid Soleimani, Zahra Sarvestani, Maryam Kaeedi, Sanaz Heydari Havadaragh · 2026

Read The Sanctuary Within: Development of CD20+ CNS Lymphoma Despite Peripheral B‐Cell Depletion by Rituximab in a Multiple Sclerosis Patient by Mohammad Hossein Harirchian, Seyed Ehsan Mohammadianinejad, Asghar Bayati, Vahid Soleimani, Zahra Sarvestani, Maryam Kaeedi, Sanaz Heydari Havadaragh (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13212263.txt.

Description

Mohammad Hossein Harirchian and colleagues describe, in 2026, a woman with multiple sclerosis whose new symptoms turned out to be a brain lymphoma rather than a relapse. She had received rituximab for years, a drug that removes B cells from the blood, yet the cancer still grew inside the nervous system.

The patient, aged 58, developed headache, vomiting, imbalance, and thinking problems over about a month. Scans looked unlike her earlier multiple sclerosis lesions, and tissue testing confirmed diffuse large B-cell lymphoma. The case warns clinicians to watch for warning signs of a second disease, even when a familiar diagnosis seems to explain new decline.

Catalog record

CREATORMohammad Hossein Harirchian, Seyed Ehsan Mohammadianinejad, Asghar Bayati, Vahid Soleimani, Zahra Sarvestani, Maryam Kaeedi, Sanaz Heydari Havadaragh
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE15 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13212263

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