Early-Life Exposure to the Cooking Oil Fume Component trans,trans-2,4-Decadienal Impairs Ocular Development and Angiogenesis in Zebrafish (Danio rerio) Larvae
Xiaoli Wu, Xinyue Zhang, Zengliang Ruan · 2026
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Description
Xiaoli Wu, Xinyue Zhang, and Zengliang Ruan tested whether a chemical in cooking oil fumes can harm developing eyes, in this 2026 study. The chemical is the main aldehyde in such fumes and a common air pollutant. Its effects on eye development had barely been studied, so the team used zebrafish larvae and human retinal cells.
Larvae injected in the eye with the chemical showed dose-linked harm: smaller eyes, less vessel growth inside the eye, and tangled retinal layers. Cell death in the eye rose with dose. Human retinal vessel cells in dishes also died back when exposed. The authors warn that early-life exposure to this fume chemical may pose a real risk to eye development.
Catalog record
| CREATOR | Xiaoli Wu, Xinyue Zhang, Zengliang Ruan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |