Evaluation of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry for Identification of Adult Schistosoma mansoni Worms and Eggs
Lucie Conrad, Franco H. Falcone, Sören L. Becker, Issa Sy · 2026
Read Evaluation of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry for Identification of Adult Schistosoma mansoni Worms and Eggs by Lucie Conrad, Franco H. Falcone, Sören L. Becker, Issa Sy (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13210210.txt.
Description
Lucie Conrad and co-authors test a fast lab method for naming a parasitic worm in a study published in 2026. The worm, Schistosoma mansoni, causes a neglected tropical disease with lasting harm. Diagnosis usually rests on finding eggs in stool under a microscope, which can miss light infections.
The method reads a protein fingerprint from the sample, a technique standard for naming bacteria. The team first built reference fingerprints from adult worms and eggs and added them to their database. After that step, blind tests named all adult worm samples and nearly all egg samples correctly. Eggs mixed into human stool, though, gave no usable signal. The authors say more work is needed before the method can serve in clinics.
Catalog record
| CREATOR | Lucie Conrad, Franco H. Falcone, Sören L. Becker, Issa Sy |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |