Mechanisms of Exercise-Mediated Regulation of the Gut–Brain Axis in Parkinson’s Disease
Xiaofan Men, Wei Wu · 2026
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Description
Xiaofan Men and Wei Wu review how exercise may protect the brain in Parkinson's disease by acting through the gut. Their 2026 review pulls together work on the gut-brain axis, the two-way link between gut microbes and the nervous system. Parkinson's involves steady loss of nerve cells, and gut changes appear early in its course.
The review traces how gut microbes may sway the disease through metabolism, immune activity, and hormone signals. Exercise, the authors argue, reshapes microbe mixes, strengthens gut and brain barriers, and boosts growth factors for nerve cells. Diet adds its own effects, and fiber-rich or Mediterranean eating may pair well with training. Different exercise types are compared for their gut-mediated benefits.
Catalog record
| CREATOR | Xiaofan Men, Wei Wu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |