Investigating the Antimycobacterial, Antibiofilm, and Antioxidant Activities of Plant Extracts Against Mycobacterium smegmatis
Ramokone Mothupi, Mashilo Matotoka, Gabriel Mashabela, Peter Masoko · 2026
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Description
Ramokone Mothupi and co-authors test plant extracts against a tuberculosis relative in this 2026 paper. The TB germ hides in biofilm-like layers that blunt drug action. Plants offer diverse chemistry that might break that defense.
Stem extracts of three South African plants were profiled for active compounds. One extract carried the most tannins and flavonoids and led on antioxidant tests. A second extract stopped bacterial growth at the lowest dose of the three. All three curbed early biofilm growth at low levels. The target germ was a safe stand-in species used in labs. Results support plant chemistry as a source of new anti-TB leads.
Catalog record
| CREATOR | Ramokone Mothupi, Mashilo Matotoka, Gabriel Mashabela, Peter Masoko |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |