Systemic Inflammation and Malnutrition Define a High-Risk Phenotype in Chronic Limb-Threatening Ischemia
Paula Luque-Linero, Prado Salamanca-Bautista, Eduardo Carmona-Nimo, Teresa Arrobas-Velilla, Francisco José Rivera-de-los-Santos, Miguel Ángel Rico-Corral · 2026
Read Systemic Inflammation and Malnutrition Define a High-Risk Phenotype in Chronic Limb-Threatening Ischemia by Paula Luque-Linero, Prado Salamanca-Bautista, Eduardo Carmona-Nimo, Teresa Arrobas-Velilla, Francisco José Rivera-de-los-Santos, Miguel Ángel Rico-Corral (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13208123.txt.
Description
Severe leg artery disease becomes far deadlier when inflammation and poor nutrition combine, a 2026 study by Paula Luque-Linero and co-authors finds. The condition, chronic limb-threatening ischemia, starves leg tissue of blood. The team tested whether blood markers of inflammation and nutritional state could sort patients by risk.
The study followed 170 patients admitted to one hospital, most of them older men with high heart risk. Within six months, about a third had a major amputation, a major heart event, or had died. Poor nutrition was the strongest single predictor of bad outcomes. Two inflammation markers also held up as independent predictors, and survival curves split clearly by risk level.
Catalog record
| CREATOR | Paula Luque-Linero, Prado Salamanca-Bautista, Eduardo Carmona-Nimo, Teresa Arrobas-Velilla, Francisco José Rivera-de-los-Santos, Miguel Ángel Rico-Corral |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |