The Role of Sigmar1 in Autophagy Regulation and Disease Therapy
Huanqing Ge, Yusi Lin, Junda Li, Renwen Zhang, Cangcang Xu · 2026
Read The Role of Sigmar1 in Autophagy Regulation and Disease Therapy by Huanqing Ge, Yusi Lin, Junda Li, Renwen Zhang, Cangcang Xu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13207866.txt.
Description
Huanqing Ge and co-authors review a chaperone protein called Sigmar1 and its role in cell self eating, in work from twenty twenty-six. The protein sits where two cell parts meet and helps cells handle stress. Self eating, or autophagy, lets cells clear worn parts and recycle them.
Sigmar1 steers the start and flow of self eating through many signal paths and partner proteins. The effect cuts both ways: it can shield nerve and heart cells under stress. In some cancers, it helps tumor cells survive and grow. Drugs that boost or block the protein are in study for both uses. The review maps the biology and the drug prospects in one place.
Catalog record
| CREATOR | Huanqing Ge, Yusi Lin, Junda Li, Renwen Zhang, Cangcang Xu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |